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Description What is know referred to as progressive vaccinia, vaccinia gangrenosum is one of the most severe complications of smallpox vaccination, and it’s almost always life threatening. Those who are most susceptible to this condition are the immunosuppressed. This image was created in 08/2003 and provided by the Centers for Disease Control and Prevention/Allen W. Mathies, MD/California Emergency Preparedness Office (Calif/EPO), Immunization Branch. For any questions about these photos, e-mail rschecht@dhs.ca.gov. For more information about Progressive Vaccinia visit CDC.
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